Relationship away from urinary salt and you may potassium excretion that have systolic hypertension from the Fat reduction Answers to End Blood pressure Sodium Demonstration

Relationship away from urinary salt and you may potassium excretion that have systolic hypertension from the Fat reduction Answers to End Blood pressure Sodium Demonstration

The 2019 National Academy of Science, Engineering and Medicine Dietary Reference Intakes (DRI) for Sodium (Na + ) and Potassium (K + ) Report concluded there remains insufficient evidence to establish a K + DRI. This study tested the hypothesis that reduced Na + and increased K + excretion will positively associate with lower blood pressure in salt sensitive (SS) and salt resistant (SR) participants in the Dietary Approaches to Stop Hypertension Sodium Trial (DASH–Sodium). Via the NHLBI BioLINCC we accessed the DASH-Sodium dataset for data on systolic blood pressure (SBP), 24-h urinary Na + and K + excretion at screening (regular patient diet; N = 186, SS N = 222 SR) and post DASH diet (N = 71 SS, N = 119 SR). The relationships between SBP, urinary Na + and K + excretion, and Na + /K + ratio were assessed via linear regression. At screening elevated urinary Na + excretion positively associated with SBP in SS (1 g increase in urinary Na + excretion = +1 0 ± 0.4 mmHg) but not SR participants, and urinary K + excretion of <1 g K + /day was associated with higher SBP in SS and SR participants. Urinary K + excretion ?1 g/day, or a decreases in urinary Na + /K + ratio, was not associated with lower SBP. Post the DASH–sodium diet intervention, SBP was reduced in SS and SR participants. However, no correlation was observed between reduced SBP and urinary K + excretion or the urinary Na + /K + ratio irrespective of the salt sensitivity of blood pressure. Our data support the DRI recommendation not to establish a K + DRI and suggest further evidence is required to support a reduced Na + /K + ratio to lower SBP.

Introduction

Blood pressure level, the most used low-communicable czy kenyancupid działa problem all over the world, signifies a serious internationally personal health issue. According to research by the 2017 Western Cardio Organization (AHA) guidance, the new incidence of blood circulation pressure in our midst people is actually projected becoming 46% ; in addition,

Association from urinary salt and you will potassium excretion with systolic hypertension throughout the Fat reduction Ways to Prevent Blood pressure Sodium Trial

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